Decreased rates of protein synthesis which occurred in rat livers perfused with amino acid-deficient medium were accompanied by a loss of
polysomesand a doubling of concentrations of ribosomal subunits and monomers as compared to unperfused liver or livers perfused with amino
acid-supplemented medium.

Link to Source:

The Journal of Biochemistry

The role of amino acids in the regulation of protein synthesis in perfused rat liver. II. Effects of amino acid deficiency on peptide
chain initiation, polysomal aggregation, and distribution of albumin mRNA…

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