…The results suggested that, when rats were fed a protein-free diet, methionine is the first limiting amino acid for liver protein synthesis.…
These results indicated that, under meal-feeding condition which may be considered more a physiological condition than force-feeding, the deficiency of
single essential amino acid generally causes the disaggregation of hepatic polysomes leading the decreased synthesis of hepatic proteins.…

Link to Source:

The Journal of Nutrition

Effects of Supplementation and Depletion of a Single Essential Amino Acid on Hepatic Polyribosome Profile in Rats

*******